This is the list of famous streets of Karachi. Major city streets that have some celebrity or historic or commercial value.
| Street | From - Towards | Lane(s) | Description |
|---|---|---|---|
| M. A. Jinnah Road aka "Bunder Road" | Tomb of Quaid-e-Azam to Tower | 3 | Named for Muhammad Ali Jinnah |
| I. I. Chundrigar Road | Shaheen Complex to Tower | 2 | Named for Ibrahim Ismail Chundrigar |
| Shara-e-Faisal | Hotel Metropole to Jinnah International Airport | 3 | Named for King Faisal of Saudi Arabia |
| Tariq Road | Allah Wala Roundabout to Shaheed e Millat Road Roundabout | 2 | Named after Tariq bin Ziyyad |
| Rashid Minhas Road | Drive-in Cinema to Shafiq Turn | 3 to 4 | Named for Pilot Officer Rashid Minhas (Nishan-e-Haider) |
| University Road | Civic Centre to Safooran Roundabout | 3 | Named for Karachi University |
| University Road | Civic Centre to Jail Roundabout | 4 to 5 | Named for Karachi University |
| Shahrah-e-Pakistan | Teen-Hati Bridge to Sohrab Goth Roundabout | 4 to 5 | - |
| Habib Ibrahim Rahimtoola Road aka "Karsaz Road" | National Stadium to Shara-e-Faisal | 3 | Named after PNS Karsaz |
| Nazimabad A Road | Lasbela Bridge to Circular Railway Line (Left-Hand Side) | 3 | Named after Khawaja Nazimuddin Second Governor General of Pakistan |
| Khayaban-e-Sher Shah Suri | Matriculation Board Office Roundabout to Sakhi Hasan Roundabout | 3 | Named after Afghan ruler of Delhi Sher Shah Suri |
| Shahrah-e-Jahangir | Nazir Chaman Plot to Bagh Mahabat Khan | 3 | - |
| Khayaban-e-Iqbal | Clifton Road Bridge to Do Talwar | 3 | - |
| Khayaban-e-Jami | Schön Circle to Khayaban-e-Ittehad | 3 | - |
| G. Alana Road aka "Maripur Road" | - to - | 3 | - |
| Khalid bin Waleed Road | Noorani Restaurant roundabout (Plot K-107) to Plot K-168 | 3 | Named for Khalid bin Waleed |
| Jamalludin Afghani Road | Television Station to Plot 1 | 3 | Named for Jamal al-Din al-Afghani |
| Allama Iqbal Road | Kashmir Road to Jheel Park | 3 | Named for Allama Iqbal |
| Sir Syed Ahmed Road | Tariq Road to kashmir road | 3 | Named for Syed Ahmed Khan |
| Shaheed-e-Millat Road | Baloch Colony Flyover to Jail Roundabout | 3 | Named for Liaquat Ali Khan |
| Chaudhari Khaliquzzaman Road | Submarine Chowk to Clifton Flyover | 3 | Named for Chaudhari Khaliquzzaman |
| Beach Avenue Road | Arabian Sea to Casino Roundabout | 3 | - |
| Khayaban-e-Saadi | Shahrah-e-Firdousi to Khayaban-e-Roomi | 3 | Named for Shaikh Saadi of Nishapur |
| Khayaban-e-Roomi | Schön Circle to Mai Kolachi | 3 | Named for Maulana Rumi |
| Nishtar Road | - to - | 3 | - |
| Alamgir Road | - to - | 3 | - |
| Burns Road | - to - | 3 | Named for Dr. James Burns, a 19th century British doctor who treated the Amirs |
| Moulvi Tamiz-Uddin Khan Road | Dr. Ziauddin Ahmed Road to Keamari Port | 3 | - |
| Tipu Sultan Road | Shara-e-Faisal to Karsaz Road | 2 | Named for Tipu Sultan, Ruler of Saragapatnum |
| Napier Road | - to - | 2 | Named for Charles Napier |
| Clifton Road | Do Talwar to Clifton Bridge | 2 | - |
| Zaibunnisa Street | Hotel Metropole to Mohammad Ali Jinnah Road | 2 | Named for Zaib-un-Nissa Hamidullah |
| Corridor I | Habib Bank, SITE to Shara-e-Faisal | 3 to 4 | First Signal Free Corridor of Pakistan |
| Corridor II | Nagan Roundabout to Shara-e-Faisal | 4 to 5 | Second Signal Free Corridor of Pakistan |
| Corridor III | Sadar Dawakhana through Safora Roundabout to Super Highway | 4 to 5 | Third Signal Free Corridor of Pakistan |
| Korangi Road | Shara-e-Faisal to Korangi Industrial Area | 4 | - |
| Sunset Boulevard | Punjab Colony to Korangi Road | 4 | - |
| Khayaban-e-Ittehad | Korangi Road to Beach Avenue | 3 | - |
| Shahrah-e-Firdousi | Casino Roundabout to Keamari Port | 2 | - |
| Shahrah-e-Ghalib | Bilawal Roundabout to Keamari Port | 3 | - |
| 5000 Road | Sakhi Hassan to Surjani Roundabout | 4 to 5 | - |
| Mai Kolachi Bypass | Jinnah Bridge/Keamari to Boat Basin | 4 | named for Mai Kolachi (Lady Kolach) an old fisher woman who settled near the delta of the Indus River to start a community. |
| Amir Khusro Road | Karsaz/Peer Pagarah House to Shaheed E Millat Road/Hill Park | 4 | named for Ab'ul Hasan Yamīn al-Dīn Khusrow, (Amir Khusrow) He was a musician, scholar and a poet . |
| Stadium Road | Along National Stadium | 4 |